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Season 2025, Episode 112: Smart Drug Delivery Systems Using Metal-Organic Frameworks | Targeted Cancer Treatment with Stimuli-Responsive Technologies

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In this episode of SciBud, join Rowan as we dive into the cutting-edge realm of metal-organic frameworks (MOFs) and their potential as smart, stimuli-responsive systems for targeted drug delivery in cancer therapy. Discover how these intricate materials could revolutionize cancer treatment by precisely delivering medication to tumors while minimizing side effects on healthy tissues. We’ll explore the unique properties of MOFs that allow them to respond to various stimuli, including changes in pH and oxidative stress levels—critical factors in the tumor microenvironment. While the promise of MOFs is clear, we'll also address the challenges they face on the journey to clinical application, including biocompatibility and data reproducibility. Plus, uncover how advances in artificial intelligence might enhance MOF research and accelerate their use in therapies. Tune in for an engaging discussion that connects the latest scientific insights with the real-world implications for cancer treatment!

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