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Season 2025, Episode 85: Predicting Graft Survival After Kidney Transplantation with Machine Learning | Social Support and Lifestyle Choices Impact Outcomes

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In this episode of SciBud, join us as we uncover a groundbreaking study from the Ethiopian National Kidney Transplantation Center that harnesses the power of artificial intelligence to predict graft survival in renal transplant recipients. With renal transplantation offering renewed hope for patients with end-stage renal disease, understanding the factors influencing graft failure is crucial. We delve into the study's innovative approach, comparing traditional statistical methods to advanced machine learning techniques, including the standout Stochastic Gradient Boosting model that achieved remarkable predictive accuracy. Discover how factors like rejection episodes, lifestyle choices, and even social support play a pivotal role in graft survival, with married individuals demonstrating significantly better outcomes. Moreover, we discuss the importance of model interpretability in clinical settings, addressing critiques of the study and highlighting its contributions to patient care. Tune in for insights into how AI can transform healthcare and improve real-world patient outcomes, all delivered with a dose of curiosity and clarity!

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